Table 1.
Effect of kinase inhibitors on mean K concentrations of tubular fluid collected from cortical collecting ducts
| Condition | [K]L at Slow Flow Rate, meq/l | [K]L at Fast Flow Rate, meq/l |
|---|---|---|
| Control | 13.9±0.5 | 8.3±0.4 |
| PKI | ||
| L | 23.4±1.9 | 10.0±0.6 |
| B | 14.3±2.6 | 6.6±0.8 |
| L+B | 12.0±1.3 | 6.8±0.6 |
| H89, L | 26.4±1.2 | 10.3±1.1 |
| Calphostin C | ||
| L | 23.2±1.9 | 8.6±0.7 |
| B | 15.9±2.2 | 8.9±0.6 |
| L+B | 27.0±1.5 | 9.5±0.4 |
| BIM+Gö6976 | ||
| L | 15.0±1.2 | 8.8±0.6 |
| B | 16.7±0.6 | 10.2±2.7 |
| L+B | 15.1±1.0 | 6.6±0.5 |
Values are means ± SE. [K]L, mean K concentration of tubular fluid; L, luminal; B, basolateral; BIM, bisindolylmaleimide.