Table 2.
Characteristics of WHISCA CEE sample at WHI baseline by treatment assignment, including age and 3MS score at WHISCA initial assessment and time from randomization
Variable | CEE | Placebo | Test of homogeneity |
---|---|---|---|
Age at WHISCA initial assessment, mean (sd), yr | 74.01 (3.73) | 74.02 (3.92) | 0.988 |
Time from WHI randomization to WHISCA initial assessment, mean (sd), yr | 3.02 (0.70) | 3.01 (0.67) | 0.841 |
3MS total score at WHI enrollment | 95.13 (3.88) | 95.49 (4.00) | 0.506 |
3MS total score at WHISCA enrollment | 95.35 (3.89) | 95.49 (4.00) | 0.596 |
Education, n (%) | 0.809 | ||
Less than high school | 26 (6.00) | 27 (5.99) | |
High school/GED | 115 (26.56) | 107 (23.73) | |
>High school, less than 4 yr college | 176 (40.65) | 191 (42.35) | |
4 yr or more of college | 116 (26.79) | 126 (27.94) | |
Race/ethnicity (%) | 0.662 | ||
White, non-Hispanic | 372 (85.91) | 392 (86.92) | |
Nonwhite/other | 61 (14.09) | 59 (13.08) | |
Body mass index, kg/m2, mean (sd) | 29.40 (6.23) | 29.21 (5.60) | 0.644 |
Smoking status, n (%) | 0.031 | ||
Never | 257 (59.77) | 244 (54.46) | |
Former | 157 (36.51) | 170 (37.95) | |
Current | 16 (3.72) | 34 (7.59) | |
Alcoholic drinks per week, n (%) | 0.098 | ||
0 | 211 (48.62) | 225 (50.00) | |
1–6 | 189 (43.55) | 173 (38.44) | |
7+ | 34 (7.83) | 52 (11.56) | |
Prior CVD, n (%) | 0.722 | ||
No | 384 (88.48) | 395 (87.39) | |
History of stroke | 5 (1.15) | 8 (1.77) | |
History of other CVD | 45 (10.37) | 49 (10.84) | |
Hypertension at WHI baseline, n (%), no/yes | 201 (46.31)/233 (53.69) | 221 (48.89)/231 (51.11) | 0.442 |
Diabetes, n (%), no/yes | 390 (89.86)/44 (10.14) | 403 (89.16)/49 (10.84) | 0.733 |
Moderate/severe vasomotor symptoms, n (%), no/yes | 391 (90.72)/40 (9.28) | 407 (90.44)/43 (9.56) | 0.889 |
Prior hormone therapy, n (%) | |||
Any prior use | 215 (49.54) | 209 (46.24) | 0.326 |
Among those with prior use: duration less than 10 yr | 134 (62.33) | 140 (66.99) | 0.316 |
CVD, Cardiovascular disease.