Table 3.

Hazard Ratio and 95% Confidence Interval Estimates.

	Group	Age 30 (95% CI)	Age 50 (95% CI)	Age 70 (95% CI)
Any HNPCC cancer (Weibull)
	Male	9.7 (0.3, 23.8)	9.7 (0.3, 23.8)	9.7 (0.3, 23.8)
	Female	54.8 (4.4, 379.8)	54.8 (4.4, 379.8)	54.8 (4.4, 379.8)
CRC (Log logistic)
	Male	34.1 (7.1, 167.0)	15.1 (3.9, 110.2)	6.8 (2.3, 66.2)
	Female	37.7 (7.5, 176.9)	32.2 (6.9, 162.1)	23.7 (5.6, 137.9)

Hazard ratio estimates at ages 30, 50 and 70 in mutation carriers compared with mutation non-carriers by sex, with corresponding 95% confidence intervals. Estimates based on the specified hazard function for age at diagnosis of any hereditary nonpolyposis colorectal cancer and colorectal cancer

HNPCC = hereditary nonpolyposis colorectal cancer

CRC = colorectal cancer