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. Author manuscript; available in PMC: 2010 Jan 31.
Published in final edited form as: Science. 2009 Jul 31;325(5940):626–628. doi: 10.1126/science.1172926

Figure 3. Kinetic model of transcription through a nucleosome.

Figure 3

The green area corresponds to on-pathway elongation (ke). The pink and blue areas represent off-pathway paused states where Pol II is backtracked; negative numbers indicate how many bases Pol II has backtracked from the elongation competent state, denoted by 0. The label u refers to the nucleosome being locally unwrapped (blue area), while w denotes the states where the nucleosome is wrapped in front of Pol II (pink area).