Fig. 5. Cardiac phenotype of Tg-DN-Lats2 mice.
(A) Immunoblot analyses of heart homogenates from Tg-DN-Lats2 (line 31) and NTg mice with anti-Lats2, anti-ANP, and anti-α actin antibodies. (B) Postmortem measurements of left ventricular weight/tibial length (LVW/TL, mg/mm, left) and right ventricular weight/tibial length (RVW/TL, mg/mm, right) in Tg-DN-Lats2 (line 31) and NTg. Values are mean ± SD. N=12-16. (C) Representative WGA staining of the LV and RV myocardium obtained from Tg-DN-Lats2 and NTg mice and the relative myocyte cross sectional area (lower panel). Values are mean ± SEM obtained from 5 experiments.
