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. Author manuscript; available in PMC: 2009 Nov 21.
Published in final edited form as: Circ Res. 2008 Oct 16;103(11):1309–1318. doi: 10.1161/CIRCRESAHA.108.180042

Fig. 6. Effects of TAC on cardiac hypertrophy in Tg-DN-Lats2 mice.

Fig. 6

Tg-DN-Lats2 (line 31) and NTg were subjected to either TAC (2 weeks) or sham operation. (A) The pressure gradient was measured after 2 weeks of TAC. (B) (left) Postmortem measurements of left ventricular weight/tibial length (LVW/TL, mg/mm, left) after TAC. (right) Percent increase in LVW/TL after TAC compared with the mean value of sham operated mice. Values are mean ± SD. N=7. (C) Representative WGA staining of the LV obtained from Tg-DN-Lats2 and NTg mice after TAC (left panel) and the relative myocyte cross sectional area (right panel). Values are mean ± SEM obtained from 5 experiments. (D) Percent TUNEL positive myocytes. Values are mean ± SEM obtained from 5 experiments. #p<0.05 vs NTg sham.