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. 2009 Nov 13;85(5):569–580. doi: 10.1016/j.ajhg.2009.09.016

Table 3.

Enzymological Parameters of the Modified NAGA

MU-α-D-Galactopyranoside-Degrading Activity
MU-α-D-N-Acetylgalactosamine-Degrading Activity
Specific Activity (mmol/h/mg) Vmax (mmol/h/mg) Km (mM) Specific Activity (μmol/h/mg)
Modified NAGA 0.5 1.0 4.8 3.0
Placenta NAGAa <0.01 - - 24
Agalsidase beta 2.3 3.8 4.0 <1.0
Agalsidase alfa 2.1 3.8 4.0 <1.0

As controls, NAGA from placenta, agalsidase beta, and agalsidase alfa were used.

a

Stored at −20°C for 30 yr.