Table 3.
Distribution of the SERPINE2 haplotypes in the cases and controls
*Wild-type allele is denoted by 1 and polymorphic allele, by 2. The order of the polymorphisms is as follows; rs16865421A>G, rs7583463A>C, rs729631C>G and rs6734100C>G; †Five haplotypes that had a frequency of less than 1% were excluded from analysis; controls, 14 (age ≤60, 8; and age >60, 6) and cases, 14 (age ≤60, 6; and age >60, 8); ‡OR (95% CI) and corresponding P values were calculated by unconditional logistic regression analysis, adjusted for age and pack-years of smoking; §OR (95% CI) and corresponding P values were calculated by unconditional logistic regression analysis, adjusted for pack-years of smoking. Corrected P value (Pc) by Hochberg and Benjamini's method; ∥Pc=0.04 and ¶Pc=0.02.