Table 2.
Inoculuma | Mouse numbers | Weeks post-inoculation | |||||
---|---|---|---|---|---|---|---|
0 | 12 | 20 | 28 | 32 | 36 | ||
Ka/W | 6 | 12.3 ± 1.0b | 39.5 ± 7.8 | 36.2 ± 6.9* | |||
Ka/O | 6 | 12.5 ± 0.9 | 44.1 ± 3.8 | 56.8 ± 5.5* | 68.8 ± 3.7** | 68.6 ± 7.5* | 61.4 ± 9.4 |
Control | 6 | 12.6 ± 0.7 | 40.1 ± 6.4 | 47.5 ± 9.0 | 49.0 ± 9.0 | 46.2 ± 6.9 | 47.8 ± 8.9 |
The asterisks indicate statistically significant differences between the scrapie-affected mice and the age-matched control mice (Student’s t test: * p < 0.05; ** p < 0.001)
aKa/scrapie weight-loss-type prion (Ka/W)- and Ka/scrapie obesity-type prion (Ka/O)-affected ICR mice at third passage were analyzed
bAverage ± standard deviation (gram)