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. 2009 Sep 11;23(11):1787–1798. doi: 10.1210/me.2009-0073

Figure 7.

Figure 7

Responses to HFD and TZD in PpargC/− mice. A, Representative growth curve of male mice (n = 8∼9 in each group) fed HFD and TZD-containing HFD. B, Adipose tissue mass from HFD and TZD-treated male Pparg+/+ (▪) and PpargC/− (□) mice expressed as percent body weight. Numbers of mice are inside bars. C, Serum glucose and insulin levels during 5-h fasting or 2-h postfeeding of male Pparg+/+ (▪) and PpargC/− (□) mice fed HFD and HFD-TZD. D, Serum glucose and insulin levels and (E) their representative IR indices during glucose tolerance tests in male littermates (n = 8∼9) fed HFD or HFD-TZD for 4 wk. *, P < 0.05; **, P < 0.01; and ***, P < 0.001 against Pparg+/+. HF, High fat.