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. 2009 Nov 20;4(11):e7932. doi: 10.1371/journal.pone.0007932

Figure 1. Strong expression of Crx mRNA is highly restricted to the retina and pineal during normal murine development.

Figure 1

RNA in situ hybridization using antisense riboprobes for Crx at developmental stage E14.5 in NMRI mouse embryos (Genepaint Set ID DA117) demonstrates strong expression in the ventricular zone of the retina (A, B) and in the developing pineal which appears as a diverticulum in the diencephalic roof of the third ventricle (C, D). Crx in the brain of a P7 C57BL/6 mouse (Genepaint Set ID MH1082) demonstrates strong expression restricted to the pineal primordium (E, F)[40], [41].