Table 3.

Expression of SORL1 isoforms relative to Braak stage.

SORL1 ISOFORM	Braak	N	Mean ± SE	P Value*
Total SORL1	0-II	20	2.167 ± 0.150	0.009
	III-V	8	1.507 ± 0.228	0.031*
	VI	29	1.537 ± 0.140	0.004*
FL-SORL1	0-II	20	2.121 ± 0.150	0.008
	III-V	8	1.470 ± 0.222	0.031*
	VI	29	1.493 ± 0.138	0.003*
Delta-2-SORL1	0-II	20	0.046 ± 0.003	0.339
	III-V	8	0.037 ± 0.006
	VI	29	0.044 ± 0.003
Delta-2-SORL1 (%)	0-II	20	2.26 ± 0.16	0.002
	III-V	8	2.48 ± 0.15	0.454*
	VI	29	3.02 ± 0.14	0.001*

For each isoform, the initial p value is the overall ANOVA p value, while the p values marked with asterisks refer to LSD post-hoc comparisons with the Braak 0-II group.