Table 5.

Expression of SORL1 isoforms in human brain as a function of rs661057 genotype.

SORL1 ISOFORM	Rs661057	N	Mean ± SE	P Value*
Total SORL1	T/T	18	2.249 ± 0.196	<0.001
	T/C	30	1.383 ± 0.086	<0.001*
	C/C	8	2.081 ± 0.295	0.552*
FL-SORL1	T/T	18	2.199 ± 0.195	<0.001
	T/C	30	1.344 ± 0.084	<0.001*
	C/C	8	2.033 ± 0.292	0.553*
Delta-2-SORL1	T/T	18	0.050 ± 0.003	0.017
	T/C	30	0.039 ± 0.002	0.007*
	C/C	8	0.048 ± 0.007	0.706*
Delta-2-SORL1 (%)	T/T	18	2.36 ± 0.20	0.072
	T/C	30	2.88 ± 0.14
	C/C	8	2.46 ± 0.28

For each isoform, the initial p value is the overall ANOVA p value, while the p values marked with asterisks refer to LSD post-hoc comparisons with the rs661057 T/T group.