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. 2009 Nov 4;7:124. doi: 10.1186/1477-7827-7-124

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Copyright © 2009 Russo et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Batimastat effects on E₂-induced changes in uterine stromal matrix density. Transmission electron microscopy analysis of endometrial stroma from animals pretreated with saline or batimastat (Bat: 40 mg/kg) 4 h prior to administration of E₂or saline injected 4 h prior to tissue collection. Panel A: Representative TEM micrographs of stromal matrix. Micrographs shown are typical from a total of 36 to 54 micrographs analyzed from 3-4 animals per treatment group; C = Collagen, S = Stromal cell, scale bar = 0.5 μm. Panel B: Quantified endometrial collagen density; one-way ANOVA, error bars represent ± SE for 3-4 animals per treatment group, total micrographs analyzed per time point range from 36 to 54; *P < 0.05 compared to saline control (Sal-Sal).