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HIV-1 binding via CCR5 induces resistance in in vitro MDM cultures. MDM binding by CCR5 chemokines mediates MDM apoptosis resistance in vitro. Indicated is the median ± SD for percentage of caspase-3 cells in five donors that were untreated (C), treated with CdCl2, and preincubated with MIP-1α (MIP1α + CdCl2) MIP1β (MIP-1β + CdCl2), and RANTES (RANTES + CdCl2).*, p ≤ 0.05.
