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. Author manuscript; available in PMC: 2009 Nov 11.
Published in final edited form as: Nat Immunol. 2004 Aug 8;5(9):927–933. doi: 10.1038/ni1105

Figure 4.

Figure 4

Effector CD8+ T cells transferred to MHC class II–deficient mice become functionally impaired. LCMV-specific effector CD8+ T cells at 8 d after infection from wild-type (a,c) or MHC class II–deficient (b,d) primary hosts were adoptively transferred into wild-type or MHC class II–deficient secondary recipients. Transferred cells were analyzed at days 3 and 60 after transfer for production of IFN-γ and IL-2 after 5 h of stimulation with GP(33–41) peptide. (a,b) Mean fluorescence intensity (MFI) for IFN-γ staining in gated region. (c,d) Percentages of IL-2-producing cells in the total IFN-γ-producing CD8+ T cell population. Data are representative of three independent studies, with two to four mice per group at each time point.