Table 2.
Case Control Allelic Association results with SNP markers selected for STAT4 gene in different racial groups. Significant allelic association results (p<10−5) and corresponding FDR q values are listed. (See supplementary Table 1 for more detail).
| SNP | Position | Minor Allele |
MAF cases |
MAF controls |
Major Allele |
OR (95% CI) | χ2 | P Value (Allelic) |
FDR q Value |
Ethnicity |
|---|---|---|---|---|---|---|---|---|---|---|
| rs10168266 | 191644049 | A | 0.251 | 0.184 | G | 1.49 (1.35–1.65) | 66.08 | 1.38E-15 | 1.90E-13 | European |
| rs10168266 | 191644049 | A | 0.400 | 0.289 | G | 1.64 (1.40–1.91) | 39.32 | 4.00E-10 | 6.87E-09 | Korean |
| rs7568275 | 191674697 | G | 0.295 | 0.225 | C | 1.45 (1.32–1.59) | 63.17 | 4.26E-15 | 2.93E-13 | European |
| rs7568275 | 191674697 | G | 0.432 | 0.329 | C | 1.54 (1.32–1.79) | 32.40 | 1.27E-08 | 1.71E-07 | Korean |
| rs7582694 | 191678365 | C | 0.296 | 0.227 | G | 1.44 (1.32–1.58) | 61.98 | 7.67E-15 | 3.51E-13 | European |
| rs7582694 | 191678365 | C | 0.433 | 0.331 | G | 1.53 (1.32–1.79) | 32.08 | 1.49E-08 | 1.71E-07 | Korean |
| rs10181656 | 191678124 | G | 0.296 | 0.227 | C | 1.44 (1.31–1.58) | 61.15 | 1.16E-14 | 3.98E-13 | European |
| rs10181656 | 191678124 | G | 0.434 | 0.331 | C | 1.53 (1.32–1.78) | 32.13 | 1.45E-08 | 1.71E-07 | Korean |
| rs3024886 | 191608694 | A | 0.252 | 0.191 | G | 1.44 (1.31–1.59) | 55.44 | 2.71E-13 | 7.45E-12 | European |
| rs3024886 | 191608694 | A | 0.509 | 0.415 | G | 1.49 (1.28–1.73) | 25.30 | 4.86E-07 | 3.93E-06 | Korean |
| rs10174238 | 191681279 | G | 0.301 | 0.235 | A | 1.41 (1.29–1.55) | 54.21 | 3.30E-13 | 7.56E-12 | European |
| rs10174238 | 191681279 | G | 0.397 | 0.303 | A | 1.52 (1.30–1.78) | 28.28 | 1.07E-07 | 1.05E-06 | Korean |
| rs3821236 | 191611003 | A | 0.244 | 0.187 | G | 1.40 (1.26–1.54) | 45.90 | 3.41E-11 | 6.69E-10 | European |
| rs3821236 | 191611003 | A | 0.510 | 0.414 | G | 1.50 (1.29–1.75) | 26.42 | 2.72E-07 | 2.34E-06 | Korean |
| rs3024861 | 191632851 | T | 0.301 | 0.247 | A | 1.32 (1.21–1.45) | 36.47 | 2.90E-09 | 4.43E-08 | European |
| rs16833215 | 191622044 | G | 0.536 | 0.434 | A | 1.53 (1.31–1.78) | 29.58 | 5.26E-08 | 5.56E-07 | Korean |
| rs16833215 | 191622044 | G | 0.339 | 0.295 | A | 1.23 (1.12–1.34) | 22.43 | 3.66E-06 | 2.79E-05 | European |
| rs3024896 | 191604961 | A | 0.468 | 0.372 | G | 1.49 (1.28–1.73) | 26.97 | 2.07E-07 | 1.89E-06 | Korean |
| rs3024896 | 191604961 | A | 0.222 | 0.185 | G | 1.26 (1.14–1.39) | 21.06 | 6.13E-06 | 4.43E-05 | European |
| rs3024877 | 191613134 | A | 0.333 | 0.294 | G | 1.21 (1.10–1.32) | 17.15 | 3.67E-05 | 1.96E-04 | European |
| rs3024847 | 191638535 | T | 0.441 | 0.399 | A | 1.19 (1.10–1.29) | 18.17 | 3.18E-05 | 1.96E-04 | European |