Fig. 2.

The effect of α β-methylene ATP and ATP on intracellular calcium concentration in preglomerular smooth muscle cells. Response of intracellular calcium concentration evoked by α β-methylene ATP or ATP (each 10 µM) in the presence of 1.8 mM extracellular calcium (a and b), in the absence of extracellular calcium (c and d) and during P2X₁ receptor blockade with NF-279 (e). The periods of exposure to α β-methylene ATP or ATP administration are indicated by the black bars. The periods of exposure to calcium-free medium or NF-279 are shown by a second set of black bars. Calcium measurements were performed using fura 2. Data were modified from an earlier report [74]