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Calculations of octanol-water log P of different tautomers of viagra and phenobarbital
| Compound | Tautomer | Structure | Octanol-water log P Program | ||
|---|---|---|---|---|---|
| CLOGP [74] | KowWin [75] | ALOGP [31] | |||
| Viagra | 1 | 
|
2.22 | 2.30 | 2.25 |
| Viagra | 2 | 
|
3.56 | 1.60 | 3.06 |
| Viagra | 3 | 
|
1.98 | 2.47 | 2.25 |
| Phenobarbital | 1 | 
|
1.36 | 1.33 | 1.32 |
| Phenobarbital | 2 | 
|
0.67 | 0.26 | 2.00 |
| Phenobarbital | 3 | 
|
0.67 | 0.93 | 2.00 |
| Phenobarbital | 4 | 
|
0.67 | 1.27 | 2.68 |
| Phenobarbital | 5 | 
|
0.67 | 1.27 | 2.68 |
