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Triptolide selectively inhibits the expression of a subset of genes involved in the immune response. RAW264.7 cells were either treated with vehicle or LPS in the presence or absence of triptolide, and microarray analyses were performed. Heat maps were generated representing cluster analyses of genes exhibiting 5-fold or greater induction by LPS (A) or 1–5-fold induction by LPS but inhibited by triptolide at least 50% (B).
