Figure 5. Roles of TLR2 and TLR4 in lung inflammatory response to high dose PLN in vivo.

Macrophage and neutrophil counts, total protein, IL-6, IL-1β, TNF-α and KC concentrations in BALF from WT, TLR2 KO and TLR4 KO mice, 6 hours after inoculation of 500 ng/mouse. Data are plotted in Box&Whiskers graph (median+interquartile range N = 8 per group). * P<0.05, † P<0.01, ‡ P<0.001 versus WT mice. Dotted line indicates mean value of PBS-treated mice.