Fig. 2.

Low doses of taxol reduce the viability of Mps1 or BubR1 depleted tumor cells. (A, C, E, G, I, and K). Quantification of colony formations of indicated cell lines treated with and without dox for 11 days. Indicated taxol concentrations were added 1 day after dox administration. Colony formation capacity of control cells (no taxol treatment) was set at 1. Average of three independent experiments is shown. (B, D, F, H, J, and L). Quantification of time-lapse movies performed as in Fig. 1E. Indicated taxol concentrations were added 1 h before filming. n = amount of cells filmed.