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. 2009 Oct 27;106(45):19174–19178. doi: 10.1073/pnas.0908711106

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Fig. 4. — Chemically simulated ON-bipolar cell light responses from wild-type and TRPM1^−/− retina. Patch clamp recording of a rod (A) and a cone (C) ON-bipolar cell in a mouse retinal slice. The patch electrode was filled with internal solution containing Alexa488 hydrazide, and the puffer pipette (visible in A) was filled with Ames media containing 600 μM CPPG and Alexa-594. Rod bipolar cell synaptic terminal is indicated by an arrow in A. Current traces at −60 mV from rod (B) and cone (D) ON-bipolar cells from wild-type and TRPM1^−/− retinas; CPPG was applied to the outer plexiform layer as indicated.