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| 129P2/Ola F1* | ||||
| Male | Female | +/+ | +/− | |
| n = | 106 | 82 | 85 | 93 |
| Ratio | 1.3∶1.0 | 0.9∶1.0 | ||
not all mice could not genotyped.
Sex and genotype ratios of the offspring of +/− mice backcrossed with wildtype mice of the 129P2/Ola and C57BL/6J genetic backgrounds are normal. Absence of live homozygous offspring from the crossing of heterozygous mice (129P2/Ola +/−×+/−) indicates that homozygous loss of Sdhd is not compatible with life.
