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. 2007 Jun 29;13:1058–1065.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Plasma soluble intracellular adhesion molecule-1 levels. The levels of soluble intracellular adhesion molecule-1 (sICAM-1) were increased with duration of diabetes. The levels of sICAM-1 are significantly higher in long term both streptozotocin-induced diabetic (STZ) rats and spontaneously diabetic Torii (SDT) rats than in Sprague-Dawley (SD) rats (p<0.05), but the difference is not significant between short term diabetic rats and controls. In addition, there was not a significant difference in the level of sICAM-1 between the STZ and the SDT rats. The data were analyzed by ANOVA with Fisher's LSD. Asterisk indicates p<0.05. Eight eyes are used in each group at each study period.