Table 3. Results of gene ontology-term based clustering.
|
UniGene name |
1 h |
3 h |
6 h |
12 h |
24 h |
48 h |
7 d |
PCR |
Abbreviated description |
|
Aminoacyl-tRNA synthetase, [David Enrichment score 3.59], translation | |||||||||
| Tars |
-1.1 |
1.3 |
-1.3 |
1.1 |
-1.7 |
-1.5 |
1 |
= |
Rat threonyl-tRNA synthetase |
| Cars |
-1.2 |
1.2 |
-1.2 |
-1.1 |
-1.8 |
-1.4 |
1 |
Cysteinyl-tRNA synthetase |
|
| Lars (prb1) |
-1.2 |
-1 |
-1.1 |
1.1 |
-1.7 |
-1.7 |
-1.1 |
= |
Leucyl-tRNA synthetase |
| Lars (prb2) |
-1.3 |
1 |
-1.1 |
1.1 |
-1.7 |
-1.6 |
-1 |
= |
Leucyl-tRNA synthetase |
| Yars |
-1 |
1.1 |
-1.1 |
-1.1 |
-1.7 |
-1.5 |
-1 |
= |
Tyrosyl-tRNA synthetase |
| Gars |
-1.2 |
-1 |
-1.1 |
1 |
-1.7 |
-1.4 |
1 |
Glycyl-tRNA synthetase |
|
| Iars (prb1) |
-1.1 |
1.1 |
-1.2 |
1 |
-1.8 |
-1.6 |
-1 |
= |
Isoleucine-tRNA synthetase |
| Iars (prb2) |
-1.3 |
1.3 |
-1.2 |
-1.1 |
-1.8 |
-1.5 |
1.1 |
= |
Isoleucine-tRNA synthetase |
| Bzw2 |
-1.1 |
-1 |
-2.3 |
1.1 |
-1.1 |
-1.3 |
1.2 |
Basic leucine zipper and W2 domains 2 |
|
| Gtpbp2 |
-1.2 |
1 |
-1.1 |
-1.1 |
1 |
-2.4 |
1 |
GTP binding protein 2 |
|
| Eif2s2 |
-1.3 |
1.2 |
-1.2 |
1.1 |
-1.4 |
-1.7 |
1 |
= |
"Rat eukaryotic translation initiation factor 2, subunit 2 beta" |
| Mthfd* |
1.2 |
1 |
-2.4 |
-1 |
-2.3 |
-2.8 |
-1.2 |
Similar to methylenetetrahydrofolate dehydrogenase (NAD) |
|
| Pop5* |
1.4 |
1 |
-2.9 |
-1.1 |
1.3 |
1.6 |
1.8 |
"Processing of precursor 5, ribonuclease P/MRP family" |
|
| Asns* |
-1 |
1.1 |
-1.1 |
-1 |
-1.7 |
-1.5 |
-1 |
= |
Asparagine synthetase |
|
Amino acid transport [David Enrichment score 1.82] | |||||||||
| Slc3a2 |
-1.1 |
1.2 |
-1.4 |
-1.1 |
-1.8 |
-1.4 |
-1.1 |
= |
"Activators of dibasic and neutral amino acid transpor, member 2" |
| Slc6a6 |
1.7 |
-1 |
1.3 |
-1.4 |
1.5 |
1.3 |
1.2 |
= |
"Neurotransmitter transporter, taurine, member 6" |
| Slc7a1 |
-1.1 |
1.4 |
-1.6 |
-1.1 |
-2.7 |
-2.2 |
-1.1 |
= |
"Cationic amino acid transporter, y+ system, member 1" |
| Slc38a2 |
-1.2 |
1 |
-1.5 |
1 |
-1.5 |
-1.7 |
-1.1 |
= |
"Solute carrier family 38, member 2" |
|
Cell death [David Enrichment score 1.88] | |||||||||
| Emp1 |
-1.5 |
-1.2 |
3.5 |
1.9 |
-1.1 |
-1.5 |
-1.3 |
Epithelial membrane protein 1 |
|
| Anxa1 |
-1.7 |
-2.3 |
3.8 |
2.1 |
1.1 |
-1.2 |
-1.1 |
= |
Annexin A1 |
| Trib3 |
-1.1 |
-1.2 |
-2.9 |
-1.2 |
-1.3 |
-1.9 |
-1 |
= |
Tribbles homolog 3 (Drosophila) |
| Lcn2 |
1.2 |
1.2 |
-1.6 |
2.3 |
2.5 |
-2 |
-1.6 |
Lipocalin 2 |
|
| Perp1 |
-1.3 |
-1.7 |
2.3 |
1.2 |
-1.2 |
-1.1 |
-1.2 |
"PERP, TP53 apoptosis effector" |
|
| Lgals7 |
-1.1 |
-2.7 |
2.9 |
-1.2 |
1 |
-1 |
-1.3 |
"Lectin, galactose binding, soluble 7" |
|
| Ccl6 |
-1.5 |
-1.6 |
2.2 |
1.2 |
-1 |
-1.1 |
-1.2 |
Chemokine (C-C motif) ligand 6 |
|
| Klf10 |
2 |
-1.1 |
1.1 |
1.1 |
1 |
-1.1 |
-1 |
Kruppel-like factor 10 |
|
|
Regulation of transcription, DNA-dependent [David Enrichment score 1.55] | |||||||||
| Atf3 |
-1.1 |
-1.3 |
-3.1 |
1.1 |
-2 |
-3.3 |
-1.2 |
= |
Activating transcription factor 3 |
| Nr4a1 |
4 |
-1.4 |
-1.3 |
-1.2 |
1 |
-1.3 |
1 |
= |
"Nuclear receptor subfamily 4, group A, member 1" |
| Nr4a3 |
5.4 |
-2.4 |
-2.1 |
1 |
-1.2 |
-1.9 |
-1.8 |
= |
"Nuclear receptor subfamily 4, group A, member 3" |
| Cebpd |
1.5 |
1.2 |
1.2 |
2 |
1.5 |
-1.9 |
-1 |
= |
"CCAAT/enhancer binding protein (C/EBP), delta" |
| Egr1 |
5 |
1.2 |
3.1 |
-1.1 |
-1.5 |
-2.1 |
-1.1 |
= |
Early growth response 1 |
| Egr4 |
2.9 |
-1.4 |
-1.1 |
-1.2 |
-1.1 |
1.1 |
-1.2 |
Early growth response 4 |
|
| Jund |
1.7 |
-1 |
-1.1 |
-1.1 |
1.1 |
-1 |
-1 |
Jun D proto-oncogene |
|
| Fgfbp1 |
-1.2 |
-1.3 |
1.5 |
1.1 |
-1.1 |
-2 |
-1 |
Fibroblast growth factor binding protein 1 |
|
| Snf1lk |
1.2 |
-2 |
-1.4 |
-1.1 |
-1 |
-1.2 |
-1.2 |
SNF1-like kinase |
|
| Zfp36 |
1.8 |
1.1 |
1.1 |
1.1 |
-1.2 |
-1.2 |
1.1 |
Zinc finger protein 36 |
|
| Arid1a |
1.2 |
1.4 |
1.2 |
1.4 |
1.4 |
2.7 |
1.5 |
AT rich interactive domain 1A (Swi1 like) |
|
| Klf4 |
2.1 |
-1 |
-1.3 |
1.2 |
-1.1 |
-1.3 |
-1.2 |
Kruppel-like factor 4 (gut) |
|
| Atf7ip |
-1.1 |
-1.1 |
-2.7 |
1.1 |
-1.6 |
-1.8 |
-1.9 |
Activating transcription factor 7 interacting protein |
|
| c-fos |
2.6 |
-1.4 |
1 |
1.1 |
-1.1 |
-1.3 |
1 |
= |
FBJ murine osteosarcoma viral oncogene homolog (Fos) |
| Cdc73 |
-1.2 |
-2.3 |
-1 |
1.2 |
1.2 |
1.1 |
-1.1 |
"Cell division cycle 73, Paf1/RNA polymerase II complex component" |
|
| Fosl2* |
1.2 |
-1.7 |
-1.2 |
1 |
-1.1 |
-1.7 |
-1.3 |
Fos-like antigen 2 |
|
| Hes5* |
-1.7 |
1 |
1.2 |
-1.1 |
-1 |
1 |
1.1 |
Hairy and enhancer of split 5 (Drosophila) |
|
| Arid2* |
1.2 |
-1.2 |
1.1 |
1 |
1.1 |
-2.3 |
-1.3 |
AT rich interactive domain 2 (Arid-rfx like) |
|
| Arid5a* |
1.8 |
-1.2 |
-1.2 |
-1 |
-1.1 |
-1.1 |
-1.1 |
AT rich interactive domain 5A (Mrf1 like) |
|
| Nab2* |
2.3 |
1.8 |
1.3 |
-1 |
1.2 |
1 |
1.1 |
= |
Ngfi-A binding protein 2 |
| Lix1* |
1.3 |
2.1 |
1 |
-1.2 |
1 |
1.3 |
1.1 |
Similar to Lix1 homolog (mouse) like (LOC499677) |
|
| Phf20* |
1.3 |
1.7 |
-1 |
-1.2 |
1.2 |
1 |
-1.1 |
Similar to PHD finger protein 20 |
|
|
Anchored to cell membrane | |||||||||
| Cp |
-1.2 |
1 |
1.2 |
2 |
1.2 |
-1.2 |
1.2 |
Ceruloplasmin |
|
| Tmprss8 |
-2.2 |
-1.8 |
1.2 |
1.2 |
1.2 |
1.1 |
1.3 |
"Transmembrane protease, serine 8 (intestinal)" |
|
|
Intermediate filament, cytoskeletal part | |||||||||
| Lmna* |
1.7 |
1.3 |
-1.1 |
-1 |
1 |
-1 |
-1 |
Lamin A |
|
| Gfap* |
1.2 |
1.6 |
1.4 |
2 |
1.8 |
-1.4 |
1.3 |
Glial fibrillary acidic protein |
|
| Emd* |
1.7 |
1.2 |
1.1 |
-1.2 |
-1.1 |
-1 |
-1 |
Emerin |
|
| Tubb6* |
1.6 |
1.7 |
1.8 |
1.2 |
1.2 |
-1.5 |
-1 |
"Tubulin, beta 6" |
|
| Pdlim3* |
1.8 |
1.7 |
1.2 |
1.2 |
1.1 |
1 |
1.2 |
PDZ and LIM domain 3 |
|
| Dsc2* |
-1.3 |
1.4 |
2.9 |
1.4 |
-1 |
-1.2 |
-1.1 |
Desmocollin 2 |
|
| Mpp2* |
1.1 |
-1.1 |
1.2 |
2.9 |
1.1 |
1.5 |
1.4 |
"Membrane protein, palmitoylated 2" |
|
| Enc1* |
1.8 |
1.2 |
1.9 |
-1.5 |
1.7 |
2.2 |
3.6 |
Ectodermal-neural cortex 1 |
|
| Nexn* |
-1.2 |
-1 |
-1 |
1 |
-1.7 |
-1.1 |
1.1 |
Nexilin |
|
| Mfap3* |
-1.1 |
2.4 |
1.1 |
-1.1 |
1.4 |
-1 |
1.4 |
Microfibrillar-associated protein 3 |
|
| Sdc1* | -1.1 | -1.8 | 2.4 | 1.1 | -1.6 | -2 | -2.4 | Syndecan 1 | |
Fold change for the different ischemic preconditioning intervals are in red color when fold change is least 1.7-times and the methodological error is p<0.01, in black when the methodological error is p<0.01. PCR column indicates whether the qPCR assay confirms the array outcome (=). UniGene names indicated by asterisk are added to the cluster on basis of other functional annotation than GOStat or DAVID. Lars and Iars were represented by two different probes (prb) on the array.