Table 3.
DRB1-DQB1 haplotype frequencies and carriage rates.
| Haplotypea |
Haplotype frequency in control population,a% |
Haplotype frequency in patients, % |
Haplotype carriage rate in patients, % |
||||||
|---|---|---|---|---|---|---|---|---|---|
|
DRB1 allele |
DRB1 allele |
RST1 infection |
RST2 infection |
RST3 infection |
RST1 infection |
RST2 infection |
RST3 infection |
Pb | |
| 0101 | 0501 | 9.1 | 3.6 | 6.9 | 18.0 | 7.1 | 13.9 | 32.0 | .018 |
| 0101 | 0504 | 0.1 | 0.0 | 2.8 | 2.0 | 0.0 | 5.6 | 4.0 | .404 |
| 0102 | 0501 | 1.4 | 5.4 | 2.8 | 2.0 | 10.7 | 5.6 | 4.0 | .327 |
| 0102 | 0504 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0103 | 0301 | 0.2 | 0.0 | 0.0 | 2.0 | 0.0 | 0.0 | 4.0 | .180 |
| 0103 | 0501 | 0.5 | 1.8 | 4.2 | 0.0 | 3.6 | 8.3 | 0.0 | .568 |
| 0301 | 0201 | 13.1 | 5.4 | 11.1 | 12.0 | 7.1 | 19.4 | 24.0 | .100 |
| 0301 | 0301 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0301 | 0602 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0313 | 0201 | 0.0 | 1.8 | 0.0 | 0.0 | 3.6 | 0.0 | 0.0 | .210 |
| 0401 | 0301 | 5.4 | 0.0 | 1.4 | 0.0 | 0.0 | 2.8 | 0.0 | .965 |
| 0401 | 0302 | 4.9 | 7.1 | 1.4 | 2.0 | 10.7 | 2.8 | 4.0 | .277 |
| 0401 | 0401 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0402 | 0302 | 1.0 | 1.8 | 1.4 | 0.0 | 3.6 | 2.8 | 0.0 | .390 |
| 0403 | 0302 | 0.4 | 0.0 | 2.8 | 2.0 | 0.0 | 5.6 | 4.0 | .404 |
| 0403 | 0304 | 0.1 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0403 | 0305 | 0.2 | 0.0 | 1.4 | 2.0 | 0.0 | 2.8 | 4.0 | .325 |
| 0403 | 0402 | 0.0 | 0.0 | 1.4 | 0.0 | 0.0 | 2.8 | 0.0 | .965 |
| 0404 | 0301 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0404 | 0302 | 3.9 | 0.0 | 4.2 | 0.0 | 0.0 | 8.3 | 0.0 | .939 |
| 0404 | 0402 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0405 | 0202 | 0.1 | 0.0 | 1.4 | 0.0 | 0.0 | 2.8 | 0.0 | .965 |
| 0405 | 0302 | 0.3 | 1.8 | 1.4 | 0.0 | 3.6 | 2.8 | 0.0 | .390 |
| 0405 | 0401 | 0.0 | 1.8 | 0.0 | 0.0 | 3.6 | 0.0 | 0.0 | .210 |
| 0406 | 0402 | 0.1 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0407 | 0301 | 0.9 | 0.0 | 0.0 | 2.0 | 0.0 | 0.0 | 4.0 | .180 |
| 0407 | 0302 | 0.1 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0408 | 0301 | 0.2 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0408 | 0304 | 0.1 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0701 | 0202 | 11.1 | 7.1 | 9.7 | 12.0 | 14.3 | 16.7 | 24.0 | .366 |
| 0701 | 0301 | 0.1 | 0.0 | 1.4 | 0.0 | 0.0 | 2.8 | 0.0 | .965 |
| 0701 | 0303 | 3.7 | 3.6 | 1.4 | 2.0 | 7.1 | 2.8 | 4.0 | .568 |
| 0801 | 0201 | 0.0 | 0.0 | 0.0 | 2.0 | 0.0 | 0.0 | 4.0 | .180 |
| 0801 | 0301 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0801 | 0302 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0801 | 0402 | 2.2 | 3.6 | 2.8 | 0.0 | 7.1 | 5.6 | 0.0 | .218 |
| 0802 | 0402 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0803 | 0301 | 0.1 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0804 | 0402 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0901 | 0201 | 0.0 | 0.0 | 1.4 | 0.0 | 0.0 | 2.8 | 0.0 | .965 |
| 0901 | 0202 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 0901 | 0303 | 0.8 | 1.8 | 0.0 | 0.0 | 3.6 | 0.0 | 0.0 | .210 |
| 1001 | 0501 | 0.7 | 1.8 | 1.4 | 0.0 | 3.6 | 2.8 | 0.0 | .390 |
| 1101 | 0301 | 5.6 | 5.4 | 5.6 | 2.0 | 10.7 | 11.1 | 4.0 | .408 |
| 1101 | 0302 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1101 | 0304 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1101 | 0502 | 0.0 | 0.0 | 1.4 | 0.0 | 0.0 | 2.8 | 0.0 | .965 |
| 1101 | 0602 | 0.1 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1102 | 0301 | 0.2 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1103 | 0301 | 0.3 | 0.0 | 1.4 | 2.0 | 0.0 | 2.8 | 4.0 | .965 |
| 1104 | 0301 | 2.7 | 1.8 | 1.4 | 4.0 | 3.6 | 2.8 | 8.0 | .454 |
| 1104 | 0502 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1104 | 0603 | 0.1 | 0.0 | 0.0 | 2.0 | 0.0 | 0.0 | 0.0 | .180 |
| 1108 | 0301 | 0.0 | 0.0 | 1.4 | 0.0 | 0.0 | 2.8 | 2.8 | .965 |
| 1201 | 0301 | 1.1 | 5.4 | 0.0 | 4.0 | 10.7 | 0.0 | 0.0 | .622 |
| 1301 | 0501 | 0.03 | 1.8 | 0.0 | 0.0 | 3.6 | 0.0 | 0.0 | .210 |
| 1301 | 0503 | 0.1 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1301 | 0603 | 5.6 | 8.9 | 4.2 | 6.0 | 17.9 | 8.3 | 8.3 | .499 |
| 1302 | 0501 | 0.0 | 1.8 | 0.0 | 0.0 | 3.6 | 0.0 | 0.0 | .210 |
| 1302 | 0602 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1302 | 0603 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1302 | 0604 | 3.4 | 1.8 | 2.8 | 6.0 | 3.6 | 5.6 | 5.6 | .230 |
| 1302 | 0609 | 0.7 | 1.8 | 1.4 | 2.0 | 3.6 | 2.8 | 2.8 | .939 |
| 1303 | 0301 | 0.7 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1305 | 0301 | 0.3 | 0.0 | 2.8 | 2.0 | 0.0 | 5.6 | 5.6 | .404 |
| 1305 | 0603 | 0.0 | 0.0 | 0.0 | 2.0 | 0.0 | 0.0 | 0.0 | .180 |
| 1401 | 0503 | 2.0 | 3.6 | 2.8 | 2.0 | 7.1 | 2.8 | 2.8 | .568 |
| 1401 | 0602 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1404 | 0503 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1407 | 0503 | 0.0 | 1.8 | 0.0 | 0.0 | 3.6 | 0.0 | 0.0 | .210 |
| 1501 | 0501 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1501 | 0502 | 0.1 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1501 | 0602 | 14.2 | 8.9 | 8.3 | 6.0 | 17.9 | 13.9 | 13.9 | .546 |
| 1501 | 0603 | 0.2 | 1.8 | 1.4 | 0.0 | 3.6 | 2.8 | 2.8 | .390 |
| 1502 | 0601 | 0.7 | 0.0 | 1.4 | 0.0 | 0.0 | 2.8 | 2.8 | .965 |
| 1502 | 0602 | 0.03 | 1.8 | 0.0 | 0.0 | 3.6 | 0.0 | 0.0 | .210 |
| 1503 | 0602 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1601 | 0502 | 1.0 | 5.4 | 1.4 | 0.0 | 10.7 | 2.8 | 2.8 | .059 |
| 1602 | 0301 | 0.03 | 0.0 | 0.0 | 0.0 | … | … | … | … |
| 1602 | 0502 | 0.2 | 0.0 | 0.0 | 0.0 | … | … | … | … |
NOTE. Boldface indicates that the allele carriage rate associated with RST2 infection was between that associated with RST1 infection and that associated with RST3 infection.
a
See [16] for definition.
b
χ2 test (1 df) for a difference in carriage rates among the ordinal Borrelia burgdorferi genotype categories.