TABLE 1.
Characteristics of 711 Participants With Coronary Disease by Fetuin-A Quartiles
| Fetuin-A Quartile |
|||||
|---|---|---|---|---|---|
| 1 (≤0.55 g/L) | 2 (0.56–0.62 g/L) | 3 (0.63–0.70 g/L) | 4 (≥0.71 g/L) | P | |
| Demographics | |||||
| Age, y | 69±12 | 69±11 | 67±11 | 64±10 | <0.001 |
| Male sex, % | 151 (84) | 150 (85) | 143 (80) | 135 (77) | 0.14 |
| Ethnicity, n (%) | |||||
| White | 116 (65) | 118 (67) | 114 (64) | 112 (64) | 0.91 |
| Black | 37 (21) | 17 (10) | 24 (13) | 28 (16) | 0.03 |
| Other | 26 (15) | 41 (23) | 40 (22) | 36 (20) | 0.16 |
| Tobacco use, n (%) | 36 (20) | 39 (22) | 30 (17) | 40 (23) | 0.51 |
| Alcohol use, n (%) | 68 (38) | 65 (37) | 45 (25) | 53 (30) | 0.03 |
| Medical history, n (%) | |||||
| Hypertension | 128 (72) | 116 (66) | 112 (63) | 119 (68) | 0.28 |
| Myocardial infarction | 92 (52) | 93 (53) | 96 (54) | 92 (53) | 0.97 |
| Angioplasty | 77 (43) | 78 (44) | 64 (36) | 64 (36) | 0.23 |
| Coronary bypass | 66 (37) | 63 (36) | 60 (34) | 58 (33) | 0.83 |
| Measurements | |||||
| Creatinine clearance, mL/min | 78±31 | 81±29 | 82±28 | 84±24 | 0.25 |
| Microalbuminuria, n (%) | 20 (30) | 16 (24) | 19 (29) | 11 (17) | 0.32 |
| Body mass index, kg/m2 | 27±5 | 27±4 | 29±5 | 29±6 | <0.001 |
| Inducible ischemia, % | 39 (23) | 43 (25) | 43 (26) | 38 (24) | 0.24 |
| Hemoglobin, g/dL | 13.5±1.4 | 13.8±1.4 | 14.1±1.3 | 14.4±1.2 | <0.001 |
| Albumin, mg/dL | 3.8±0.4 | 3.9±0.3 | 3.9±0.3 | 4.0±0.3 | <0.001 |
| CRP, mg/dL* | 2.0 (0.6–4.5) | 1.8 (0.6–3.8) | 2.5 (0.9–5.3) | 2.8 (1.1–5.2) | 0.02 |
| Fibrinogen, mg/dL | 373±89 | 379±87 | 396±97 | 394±81 | 0.04 |
| Pulse pressure, mm Hg | 56±13 | 58±18 | 58±16 | 56±15 | 0.97 |
Values are mean±SD when appropriate.
*
Median (intraquartile range).