Table 1.
Characteristics of 985 participants by level of C-reactive protein (CRP)
| Variable | CRP |
p Value | ||
|---|---|---|---|---|
| <1 mg/L (n = 262) | 1–3 mg/L (n = 333) | >3 mg/L (n = 390) | ||
| Age (yrs) | 66 ± 11 | 68 ± 11 | 66 ± 11 | 0.02 |
| Men | 224 (86%) | 283 (85%) | 295 (76%) | 0.001 |
| White | 151 (58%) | 208 (62%) | 236 (61%) | 0.52 |
| Married | 131 (50%) | 137 (41%) | 153 (39%) | 0.02 |
| Current smoking | 38 (15%) | 50 (15%) | 107 (27%) | <0.0001 |
| Regular alcohol use | 77 (30%) | 100 (30%) | 108 (28%) | 0.78 |
| Hypertension | 176 (68%) | 234 (70%) | 284 (73%) | 0.36 |
| Diabetes mellitus | 55 (21%) | 95 (29%) | 110 (28%) | 0.07 |
| Congestive heart failure | 33 (13%) | 53 (16%) | 87 (22%) | 0.004 |
| Angina weekly or more | 94 (36%) | 114 (34%) | 146 (38%) | 0.65 |
| Previous myocardial infarction | 136 (52%) | 188 (57%) | 203 (52%) | 0.37 |
| Previous stroke | 34 (13%) | 49 (15%) | 55 (14%) | 0.85 |
| Previous coronary artery bypass grafting | 101 (39%) | 123 (37%) | 125 (32%) | 0.18 |
| Previous coronary angioplasty | 106 (41%) | 133 (40%) | 146 (38%) | 0.67 |
| Current depression | 58 (22%) | 75 (23%) | 84 (22%) | 0.94 |
| Not at all or a little physically active | 63 (24%) | 112 (34%) | 185 (48%) | <0.0001 |
| β-Blocker use | 160 (61%) | 191 (57%) | 214 (55%) | 0.29 |
| Renin-angiotensin system inhibitor use | 136 (52%) | 180 (54%) | 189 (48%) | 0.31 |
| Diuretics (loop or thiazide) use | 57 (22%) | 90 (27%) | 143 (37%) | 0.0001 |
| Statin use | 177 (68%) | 230 (69%) | 226 (58%) | 0.003 |
| Aspirin use | 216 (82%) | 257 (77%) | 288 (74%) | 0.03 |
| Hormone replacement therapy use | 7 (3%) | 9 (3%) | 30 (8%) | 0.001 |
| Ejection fraction (%) | 0.62 ± 0.09 | 0.62 ± 0.10 | 0.61 ± 0.10 | 0.33 |
| Wall motion score index | 1.14 ± .31 | 1.17 ± .34 | 1.19 ± .39 | 0.22 |
| Systolic blood pressure (mm Hg) | 129 ± 20 | 132 ± 20 | 136 ± 22 | <0.0001 |
| Diastolic blood pressure (mm Hg) | 73 ± 12 | 75 ± 11 | 76 ± 11 | 0.005 |
| Total cholesterol (mg/dl) | 171 ± 37 | 177 ± 43 | 183 ± 46 | 0.001 |
| High-density lipoprotein (mg/dl) | 47.8 ± 15 | 46 ± 14 | 44 ± 13 | 0.004 |
| Low-density lipoprotein (mg/dl) | 96.5 ± 26 | 104 ± 33 | 110 ± 38 | <0.0001 |
| Creatinine clearance (ml/min) | 86 ± 28 | 81 ± 28 | 78 ± 29 | 0.001 |
| Body mass index (kg/m2) | 27 ± 4.1 | 28 ± 5 | 30 ± 6 | <0.0001 |
| Triglycerides (mg/dl) | 136 ± 157 | 137 ± 120 | 147 ± 113 | 0.47 |
Values are means ± SD or numbers of patients (percentages).