Table 2. SKN-1-downregulated genes identified under non-stressed conditions.
The top 35 genes for which expression was differentially increased in skn-1(RNAi) animals under non-stressed conditions (SKN-1-downregulated genes), as ranked by SAM score. These and the other SKN-1-downregulated genes we identified (63 total) are listed by functional group in Table S2.
| Sequence Name | Gene Name | KOG Title or Protein Domain | Score |
|---|---|---|---|
| F42G2.4 | fbxa-182 | Protein containing an F-box motif | −9.335 |
| T26F2.2 | Uncharacterized protein | −6.858 | |
| C31B8.4 | Uncharacterized protein | −6.611 | |
| Y39B6A.24 | Aspartyl protease | −6.555 | |
| ZC196.4 | Protein of unknown function DUF713 | −6.389 | |
| C17H1.7 | Uncharacterized protein | −6.218 | |
| Y47H9C.1 | Protein of unknown function DUF274 | −6.137 | |
| C06E1.1 | Protein involved in membrane traffic (YOP1/TB2/DP1/HVA22 family) | −6.065 | |
| Y69A2AR.12 | Uncharacterized protein | −5.562 | |
| F15B9.6 | Uncharacterized protein | −5.402 | |
| Y75B8A.32 | Predicted DNA-binding protein | −5.093 | |
| F15D3.8 | Uncharacterized protein | −5.031 | |
| F47H4.8 | fbxa-188 | Protein containing an F-box motif | −5.009 |
| M01G12.12 | rrf-2 | Putative RNA-directed RNA polymerase QDE-1 required for posttranscriptional gene silencing and RNAi | −4.913 |
| K08H10.1 | lea-1 | Protein that is predicted to be hydrophilic and heat-resistant | −4.785 |
| Y46G5A.20 | Uncharacterized protein | −4.639 | |
| Y6E2A.4 | Protein of unknown function DUF713 | −4.611 | |
| Y41C4A.11 | Vesicle coat complex COPI, beta’ subunit | −4.424 | |
| F45E4.1 | arf-1.1 | GTP-binding ADP-ribosylation factor Arf1 | −4.408 |
| F47H4.10 | skr-5 | SCF ubiquitin ligase, Skp1 component | −4.021 |
| C54G6.5 | spp-17 | Saposin-like Protein family | −4.009 |
| Y43C5A.3 | Uncharacterized protein | −3.989 | |
| B0024.4 | Protein of unknown function DUF274 | −3.929 | |
| W03D2.6 | C-type lectin | −3.826 | |
| F58B3.3 | lys-6 | N-acetylmuraminidase/lysozyme | −3.758 |
| Y51B9A.9 | Jun-N-terminal kinase (JNK) | −3.546 | |
| C06E4.8 | Uncharacterized protein | −3.527 | |
| F23F12.3 | Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily) | −3.474 | |
| F25B3.5 | Uncharacterized protein | −3.464 | |
| F58F9.7 | Pristanoyl-CoA/acyl-CoA oxidase | −3.452 | |
| C01G6.7 | Acyl-CoA synthetase | −3.428 | |
| ZK1251.2 | ins-7 | Insulin-like peptides | −3.423 |
| C45B11.3 | dhs-18 | Reductases with broad range of substrate specificities | −3.295 |
| F02C12.5 | cyp-13B1 | Cytochrome P450 CYP3/CYP5/CYP6/CYP9 subfamilies | −3.276 |
| C04F12.1 | Translation initiation factor 2C (eIF-2C) and related proteins | −3.263 |