Table 3. Summary of Lifespan Effects of SKN-1 Downregulated Genes.

For details of lifespan assay conditions and analysis see Experimental Procedures, Table S11, and Table S12.

		Expt 1		Expt 2		Expt 3
Gene	Gene name	% of control	p-value	% of control	p-value	% of control	p-value
C54G6.5**	spp-17	121.7	<0.0001	125.2	<0.0001	119.3	<0.0001
C01G6.7**	acs-7	112.6	<0.0001	116.1	<0.0001	121.4	<0.0001
Y43C5A.3**		121.7	<0.0001	114.0	<0.0001	113.6	0.006
F25B3.5*		126.6	<0.0001	113.3	<0.0001	110.9	0.0209
F23F12.3**		116.1	<0.0001	113.3	0.0002	125.1	<0.0001
Y47H9C.1**		113.3	<0.0001	112.6	<0.0001	119.8	<0.0001
ZK1251.2**	ins-7	111.2	0.0006	112.6	<0.0001	122.3	<0.0001
B0024.4*		120.3	<0.0001	110.5	<0.0001	103.4	0.5417
F58F9.7*		118.2	<0.0001	110.5	<0.0001	112.6	0.0151
F58B3.3	lys-6	116.8	<0.0001	110.5	0.0128
F02C12.5*	cyp-13B	127.3	<0.0001	109.1	<0.0001	110.4	0.039
C31B8.4**		116.8	<0.0001	109.1	<0.0001	121.6	<0.0001
F15B9.6**		125.2	<0.0001	108.4	<0.0001	122.7	<0.0001
ZC196.4*		101.4	0.898	108.4	0.0003	120.6	0.0001
Y46G5A.20**		130.8	<0.0001	107.7	0.0001	120.0	<0.0001
F45E4.1**	arf-1.1	111.2	0.0002	107.7	<0.0001	117.5	0.0008
F47H4.8*	fbxa-188	117.5	<0.0001	107.0	0.0208	120.0	0.0002
F15D3.8*		112.6	<0.0001	107.0	0.0087	100.0
Y41C4A.11**		121.7	<0.0001	105.6	0.0005	123.4	<0.0001
Y6E2A.4		113.3	<0.0001	105.6	0.8425
C17H1.7*		124.5	<0.0001	104.9	0.0004	109.9	0.0435
F47H4.10*	skr-5	116.1	<0.0001	104.2	0.0079
Y51B9A.9		104.2	0.0858	104.2	0.0106
Y39B6A.24		112.6	<0.0001	102.8	0.0508
K08H10.1*	lea-1	120.3	<0.0001	97.2	0.867	112.9	0.007
M01G12.12	rrf-2	114.0	<0.0001	93.7	0.6139

^**Significant (p<0.01) in all three trials.

^*Significant (p<0.01) in two trials.

% of control refers to the mean lifespan. Functional information for these genes is available in Table 2.