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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Bioorg Med Chem Lett. 2009 Aug 3;19(19):5773–5777. doi: 10.1016/j.bmcl.2009.07.150

Table 3.

Time-dependant degradation of pyrazole series 7 and 10a

graphic file with name nihms141256f9.jpg

Compounds Degradation of compound w.r.t standard t1/2 (min)
7a 90
7b 90
7d 255
7e 450
7g 150
7n 300
10a 900
10c 90
a

The compounds were dissolved in <10% DMSO, pH 8 buffer (1mM) and Chlorpromazine (15mM).