Table 3.
Time-dependant degradation of pyrazole series 7 and 10a
![]() | |
|---|---|
| Compounds | Degradation of compound w.r.t standard t1/2 (min) |
| 7a | 90 |
| 7b | 90 |
| 7d | 255 |
| 7e | 450 |
| 7g | 150 |
| 7n | 300 |
| 10a | 900 |
| 10c | 90 |
The compounds were dissolved in <10% DMSO, pH 8 buffer (1mM) and Chlorpromazine (15mM).
