Plasma THC levels when marijuana was smoked as joints and blunts averaged across all post-smoking time points analyzed for all participants (panel a) (joints, ν; blunts, σ), and men (panel b) and women (panel c) analyzed separately (joints, □; blunts, ■). Significant differences between joints and blunts indicated as follows: *, p ≤ 0.05; **, p ≤ 0.01. Significant differences between placebo and active marijuana is indicated as follows: #, p ≤ 0.05; ##, p ≤ 0.01.