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Heart rate (panel a) and expired carbon monoxide (panel b) averaged across all post-smoking time points when marijuana was smoked as joints and blunts for all participants (joints, ν; blunts, σ), and men and women analyzed separately (joints, □; blunts, ■). Significant differences between joints and blunts indicated as follows: *, p ≤ 0.05; **, p ≤ 0.01; ***, p ≤ 0.001. Significant differences between placebo and active marijuana is indicated as follows: #, p ≤ 0.05.
