Table 1.
Baseline characteristics of the 48,785 patients included in the analysis, stratified by mortality and treatment failure, from the National Free Antiretroviral Treatment Program, China, June 2002 – August 2008.
| Total (No.=48785) |
Alive (No.=42295) |
Dead (No.=6490) |
Total (No.=31070) |
Treatment Success (No.=23373) |
Treatment Failure (No.=7697) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. | Value | No. | Value | No. | Value | P Value |
No. | Value | No. | Value | No. | Value | P Value |
|
| Age, median (IQR), years | 48785 | 38 (33-46) | 42295 | 38 (33-45) | 6490 | 40 (34-49) | <0.001 | 31070 | 38 (33-46) | 23373 | 38 (33-45) | 7697 | 39 (34-47) | <0.001 |
| Female, No. (%) | 48761 | 20441 (42) | 42273 | 18087 (43) | 6488 | 2354 (36) | <0.001 | 31061 | 13526 (44) | 23366 | 10345 (44) | 7695 | 3181 (41) | <0.001 |
| Married, No. (%) | 48728 | 36302 (75) | 42246 | 31441 (74) | 6482 | 4861 (75) | 0.33 | 31049 | 23590 (76) | 23356 | 17683 (76) | 7693 | 5907 (77) | 0.056 |
| Infection route, Former plasma donors/blood transfusion, No. (%) | 48785 | 25778 (53) | 42295 | 21283 (50) | 6490 | 4495 (69) | <0.001 | 31070 | 17222 (55) | 23373 | 12106 (52) | 7697 | 5116 (67) | <0.001 |
| Weight, median (IQR), kg | ||||||||||||||
| Female | 20381 | 53 (48-59) | 18037 | 53 (48-60) | 2344 | 50 (45-55) | <0.001 | 13499 | 53 (48-60) | 10325 | 53 (48-60) | 3174 | 53 (48-60) | 0.11 |
| Male | 28229 | 59 (52-64) | 24113 | 59 (53-65) | 4116 | 55 (50-61) | <0.001 | 17481 | 60 (54-65) | 12983 | 60 (53-65) | 4498 | 60 (54-65) | 0.69 |
| Baseline CD4 cell count (/μL), median (IQR) | 30222 | 118 (37-203) | 27319 | 127 (42-208) | 2903 | 47 (15-121) | <0.001 | 19738 | 122 (41-203) | 14845 | 117 (42-192) | 4893 | 146 (36-251) | 0.001 |
| CD4 <50/μL, No. (%) | 9037 (30) | 7543 (28) | 1494 (52) | <0.001 | 5621 (29) | 4170 (28) | 1451 (30) | 0.035 | ||||||
| Hemoglobin, median (IQR), g/dL | 42333 | 12 (11-14) | 37041 | 12 (11-14) | 5292 | 11 (10-13) | <0.001 | 27149 | 12 (11-14) | 20598 | 12 (11-14) | 6551 | 12 (11-14) | 0.27 |
| Hemoglobin <8 g/dL, No. (%) | 2070 (5) | 1554 (4) | 516 (10) | <0.001 | 1100 (4) | 807 (4) | 293 (5) | 0.047 | ||||||
| ALT (SGPT), median (IQR), U/L | 39720 | 28 (19-42) | 34977 | 28 (19-42) | 4743 | 30 (19-44) | 0.001 | 25466 | 28 (19-42) | 19525 | 28 (19-42) | 5941 | 28 (19-42) | 0.39 |
| ALT >100 U/L, No. (%) | 1370 (3.4) | 1187 (3) | 183 (4) | 0.10 | 834 (3) | 646 (3) | 188 (3) | 0.59 | ||||||
| Number of baseline symptom categories | 48722 | 42244 | 6478 | 31042 | 23350 | 7692 | ||||||||
| 0 | 9102 (19) | 8647 (21) | 455 (7) | <0.001 | 5916 (19) | 4736 (20) | 1180 (15) | |||||||
| 1 | 7533 (16) | 6898 (16) | 635 (10) | 4932 (16) | 3793 (16) | 1139 (15) | ||||||||
| 2-3 | 19636 (40) | 16747 (40) | 2889 (45) | 12324 (40) | 9187 (39) | 3137 (41) | ||||||||
| 4-5 | 12451 (26) | 9952 (24) | 2499 (39) | 7870 (25) | 5634 (24) | 2236 (29) | <0.001 | |||||||
Note: IQR=interquartile range; SD=standard deviation; ALT=alanine aminotransferase; SGPT=serum glutamic pyruvic transaminase