Table 5.
Histological features of biliary atresia and other intrahepatic cholestasis (n)
| Histological features | Biliary atresia | Intrahepatic cholestasis1 |
| Ductular proliferation | ||
| None | 1 | 31 |
| Mild | 2 | 11 |
| Moderate | 3 | 4 |
| Severe | 27 | 2 |
| Bile plug in bile ductules | ||
| Absent | 10 | 42 |
| Present | 21 | 7 |
| Porto-portal bridging | ||
| None | 1 | 33 |
| < 50% of portal tracts | 8 | 6 |
| > 50% of portal tracts | 22 | 6 |
| Lymphocytic infiltration | ||
| Moderate to severe | 7 | 23 |
| Mild | 16 | 24 |
| Absent or mild | 10 | 3 |
| Neutrophilic infiltration | ||
| Moderate to severe | 3 | 15 |
| Absent to mild | 30 | 35 |
| Giant cell transformation of hepatocytes | ||
| Diffuse | 1 | 16 |
| Only around central vein | 13 | 23 |
| None | 19 | 11 |
| Hepatocytes swelling | ||
| Hepatocytes swelling | 4 | 27 |
| Mild/focal | 13 | 22 |
| None | 16 | 1 |
1
Including cytomegalovirus hepatitis (n = 6), progressive familial intrahepatic cholestasis (n = 4), Alagille syndrome (n = 1), TPN-associated cholestasis (n = 1), hypothyroidism (n = 1), Caroli disease (n = 1), severe perinatal asphyxia (n = 1), idiopathic neonatal hepatitis (n = 35).