Table 7.

Sensitivity, specificity, positive and negative predictive values of various histological features in differentiating non-biliary atresia from biliary atresia

Histological features	Non-BA	BA	Sensitivity for BA (%)	Specificity for BA (%)	Positive PV for non-BA & negative PV for BA (%)	Negative PV for non-BA & positive PV for BA (%)
Lymphocytic infiltration
Moderate to severe	23	7	23/50 (46)	26/33 (79)	23/30 (77)	26/53 (49)
Absent or mild	27	26
Neutrophilic infiltration
Moderate to severe	15	3	15/50 (30)	30/33 (91)	15/18 (83)	30/65 (46)
Absent to mild	35	30
Giant cell transformation of hepatocytes
Diffuse	16	1	16/50 (32)	32/33 (97)	16/17 (94)	32/66 (48)
None or around central vein	34	32
Hepatocytes swelling
Periportal or diffuse	27	4	27/50 (54)	29/33 (88)	27/31 (87)	29/52 (56)
None or mild/focal	23	29