Table 1.
Chemokines and their receptors
| Chemokine receptor | Chemokine ligands | Target cells | |
| Subfamily CC | |||
| CCR1 | CCL3, CCL5, CCL7, CCL14 | T cells, monocytes, basophils and eosinophils | |
| CCR2 | CCL2, CCL8, CC7, CCL13, CCL16 | Memory T cells, monocytes and dendritic cells | |
| CCR3 | CCL11, CCL13, CCL7, CCL5, CCL8, CCL13 | Eosinophils, basophils, mast cells, T helper 2 cells and platelets | |
| CCR4 | CCL17, CCL22 | T helper 2 cells, dendritic cells, basophils, macrophages and platelets | |
| CCR5 | CCL3, CCL4, CCL5, CCL11, CCL14, CCL16 | T cells, monocytes | |
| CCR6 | CCL20 | T cells, B cells and dendritic cells | |
| CCR7 | CCL19, CCL21 | T cells and dendritic cells | |
| CCR9 | CCL25 | T cells, plasma cells | |
| CCR10 | CCL27, CCL28 | T cells | |
| Subfamily CXC | |||
| CXCR1 | CXCL8, CXCL6 | Neutrophils and monocytes | |
| CXCR2 | CXCL8, CXCL1, CXCL2, CXCL3, CXCL5, CXCL6 | Neutrophils, monocytes and vascular endothelial cells | |
| CXCR3-A | CXCL9, CXCL10, CXCL11 | T helper 1 cells, mast cells and mesangial cells | |
| CXCR3-B | CXCL4, CXCL9, CXCL10, CXCL11 | Neoplastic cells and vascular endothelial cells | |
| CXCR4 | CXCL12 | Expressed in multiple cells | |
| CXCR5 | CXCL13 | B cells and T helper cells | |
| CXCR6 | CXCL16 | CD8+ cells, natural killer cells and memory CD4+ cells | |
| Subfamily CX3C | |||
| CX3CR1 | CX3CL1 | Macrophages and smooth muscle cells | |
| Subfamily XC | |||
| XCR1 | XCL1, XCL2 | T cells and natural killer cells |