Table I.

Kinetic Parameters for Deamidation in Model Peptides and in the Intact Fc Fragment

Parametera	Value (days)−1	S.E.b (days)−1	CV (%)c
Model peptides
k1p	0.206	0.002	0.9
k2p	0.69	0.05	7.2
k3p	2.8	0.2	7.1
Intact Fc fragmentd
k1	0.0039	0.00006	1.5
k2	0.0025	0.00006	2.4

^aValues determined by nonlinear regression of data in Figures 6 and 7. See Figure 5 for kinetic schemes and parameter definitions.

^bS.E. = standard error of regression.

^cCV (%) = percent coefficient of variation, 100 × (S.E.)/value.

^dRegression assumes k₁ = k₄ and k₂ = k₃; see Figure 5.