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. 2009 Jul 22;102(4):2176–2183. doi: 10.1152/jn.00463.2009

Fig. 1.

Fig. 1.

Examples of units isolated using histamine search strategy. A: peristimulus-time histogram (PSTH; bins 1 s) of a unit response to histamine (left PSTH). This mechanically insensitive unit responded weakly, if at all, to subsequent intradermal injection of SLIGRL-NH2 or to topical application of mustard oil (MO) or intradermal capsaicin. Inset: left: drawing of left hindpaw with arrow indicating intradermal injection site. Right: drawing of histological section showing recording site (open circle) in lamina I of superficial dorsal horn. B: a different wide dynamic range (WDR) lamina I unit that responded weakly to histamine and more strongly to SLIGRL-NH2 (format as in A). This unit also responded robustly to capsaicin and weakly to mustard oil. Top left inset: drawing of left hindpaw receptive field (gray) and injection site (arrow). C: a different WDR lamina I unit that responded equally to intradermal histamine and SLIGRL-NH2. This unit also responded phasically to capsaicin and mustard oil (format as in A and B).