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Schematic showing 3 possible mechanisms that could produce a cortical gate. In each of these scenarios, transcranial magnetic stimulation (TMS) is envisioned as producing an activation in 1 cortical area (A and B). One of 3 possible mechanisms (C–E) then greatly diminishes the propagation of the evoked activity to other cortical areas (F and G). The mechanisms illustrated here are tested in our thalamocortical network.
