Fig. 8.

High degree of cDNA integration results in cell lysis. Cell death was estimated 48 h PI (A) or 96 h PI (B) in peptide-treated H9 lymphocytes infected by ΔEnv HIV-1 or 48 h PI in peptide-treated H9 lymphocytes infected by Rev M10 (C) as well as at different times in cells infected by the WT virus (D). (E) as in (A) but peptides were at different times PI. (F) as in (A) but cells were double infected with ΔEnv HIV-1 (second infection was 12 h post first infection). (G) as in (A) but cells were infected by IN mut D64, 116N HIV-1. P < 0.05.