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. 2009 Jul 8;30(22):2722–2732. doi: 10.1093/eurheartj/ehp265

Table 3.

Infarct parameters before and 12 weeks after surgery

Week 12 Week 24 P-value
MI size (% of LV mass) Placebo 17.3 ± 1.6 18.5 ± 1.2 0.57
Low-dose MSC 16.3 ± 1.1 12.5 ± 1.0 0.06*
High-dose MSC 18.2 ± 0.9 14.4 ± 1.0 0.018*

Infarct volume (cc) Placebo 8.0 ± 0.9 8.8 ± 1.1 0.59
Low-dose MSC 7.3 ± 0.5 6.0 ± 1.2 0.37
High-dose MSC 8.2 ± 0.4 6.6 ± 0.5 0.03

LV mass (g) Placebo 45.9 ± 1.4 47.2 ± 3.6 0.75
Low-dose MSC 45.1 ± 2.1 47.2 ± 4.9 0.71
High-dose MSC 45.3 ± 0.7 46.1 ± 1.2 0.58

Circumferential extent (% LV circumference) Placebo 43.8 ± 1.4 45.3 ± 0.8 0.39
Low-dose MSC 44.7 ± 2.3 36.4 ± 3.3 0.11*
High-dose MSC 44.3 ± 2.1 31.4 ± 1.3 0.001*

Infarct thickness (mm) Placebo 4.0 ± 0.1 3.6 ± 0.2 0.12
Low-dose MSC 3.3 ± 0.1 4.9 ± 0.5 0.035*
High-dose MSC 3.9 ± 0.2 4.9 ± 0.4 0.049*

Remote thickness (mm) Placebo 7.1 ± 0.5 7.4 ± 0.5 0.69
Low-dose MSC 6.9 ± 0.5 7.6 ± 0.5 0.38
High-dose MSC 6.6 ± 0.5 6.9 ± 0.3 0.62

All values were calculated based on delayed contrast enhanced magnetic resonance imaging.

MI, myocardial infarction; LV, left ventricular.

*P < 0.05 vs. placebo.

P < 0.05 week 12 vs. week 24.

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