Figure 2.
(a) SauLigA active site. The adenine ribose moiety (magenta) is positioned from the crystal structure of the EfaLigA–NAD complex. The critical side chains are shown in ball-and-stick representation and labeled, with hydrogen bonds shown as dashed lines. Residues involved in interactions with adenine are colored green. (b) A surface view of SauLigA with modeled adenosine (magenta) looking into the unique ‘C2 tunnel’. The hydrophobic residues are shown as green ball-and-stick representations.
