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Electron density for the Schiff base between Lys165 and pyruvate. The planarity of the 2F o − F c map (contoured at 1.0 r.m.s.) is consistent with the formation of a Schiff base between Lys165 and pyruvate. The hydrogen-bond network between pyruvate and Thr48 and Ser47 and between Tyr137, Ser47 and a water is well conserved in all members of the NAL family.
