Table 4. SPR data for rabbit and human FGF-1 (‘analyte’) with human FGFR1c D2/D3 extracellular domains (‘ligand’) attached to an SA chip (Biacore).

	ka (M−1 s−1)	kd (s−1)	Kd† (M)
Human FGF-1	2.14 ± 0.25 × 106	17.3 ± 1.9 × 10−3	8.07 ± 0.9 × 10−9
Rabbit FGF-1	1.66 ± 0.20 × 106	19.6 ± 2.1 × 10−3	11.8 ± 0.7 × 10−9

^†Derived kinetic constants are for a global fit to all analyte-concentration data; standard deviation values are obtained from a comparison of the individual analyte-concentration fitting results.