Figure 1.

Predicted domain organization of porcine adenovirus type 4 NADC-1 strain fibre. The amino-acid sequence (single-letter code; above) and a schematic drawing (below) are shown. The predicted virus-binding tail (residues 1–37) is shown in black, the shaft domain (40–120) in white, the predicted head domain (121–287) in light grey, the RGD-containing domain (292–392) in white and the predicted galectin-like domain (393–681) in dark grey. The putative integrin-binding RGD sequence is indicated in bold in the sequence and with an asterisk in the drawing. The sequences expressed and crystallized (116–291 and 393–703) are underlined; they correspond to the head and galectin-like domains plus a few N-terminal and C-­terminal amino acids. It should be noted that in the absence of electron-microscopy data the relative orientations and dimensions of the domains are unknown.