Figure 2.

Superimposition of the molecular-replacement solution of the RA15–NLV–A2 complex (coloured) on the RA14–NLV–A2 complex structure (white). Superposition was performed on the α1α2 HLA-A2 domain. (a) Overall view of the superimposition, (b) closer view of the TCR–NLV–A2 interface. CDRs are coloured as follows: CDR1α, green; CDR2α, red; CDR3α, dark blue; CDR1β, pale green; CDR2β, orange; CDR3β, light blue. The NLV peptide is represented by violet sticks, the HLA-A2 α1 helix in gold and the α2 helix in silver.