Table 2.
Prospective, Randomized, Controlled Trials for the Treatment of Stone Recurrence With Alkali Citrate Therapy Lasting at Least 1 Year
| Study | Duration (mo) | Rx | n | Dropout Rate (%) | Remission Rate (%) | Average Increase in Citrate Excretion (%) |
| Barcelo et al.98 | 36 | K-Citrate | 18 | 36 | 72.2 | 77 |
| Control | 20 | 31 | 20 | 0 | ||
| Hofbauer et al.99 | 36 | Na-K-Citrate | 22 | 36 | 31* | 75 |
| Control | 16 | 12 | 27 | 0 | ||
| Ettinger et al.93 | ≦37 | K-Mg-Citrate | 31 | 48 | 87.1 | 31 |
| Control | 33 | 24 | 36.5 | 0 | ||
| Soygur et al.100 | 12 | K-Citrate | 28 | NS | 100 | 115 |
| Control | 28 | NS | 71.4 | NS |
No statistically significant difference.
NS, not stated.