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. 2009 Sep 3;112(2):331–343. doi: 10.1093/toxsci/kfp207

FIG. 2.

FIG. 2.

The absolute weight of the bulbospongiosus muscle (A), levator ani muscle (B), and penis (C), the length of the penis (D), the diameter of the penis (E), and the concentration of plasma testosterone (F) in adult rats treated neonatally with EE at a dose of 10 ng or 100 ng or 1 μg or 10 μg/rat on every other day from postnatal days 1 to 11. Note a significant reduction in the weight of the bulbospongiosus muscle in the > 10-ng (1 μg/kg) groups, in the weight, length, and diameter of the penis in the > 100-ng groups, and in the weight of the levator ani muscle and the concentration of plasma testosterone in the > 1-μg groups. Data are expressed as mean ± SEM. Means with different superscripts are significantly (p < 0.05) different from controls. BS, bulbospongiosus; LA, levator ani; T, testosterone.